I would be willing to trade Skubal for a kings ransom. Unfortunately, that is not an option. Look at the Burnes trade for the Brewers, the best player they got was Joey Ortiz, who was the 45h ranked prospect on fangraphs, and he is projected as a 2 WAR player entering his age 27 season. He's a solid player, but he is not an impact player, and not a player that meaningfully changes the outlook of your franchise over a 3-5 year period. If you have a good scouting and development organization, and don't have an incredibly cheap and deadbeat ownership, you will have no problem consistently acquiring/developing solid 2 WAR guys, missing out on a guy like that will never be what holds your team back.
I checked the fangraphs top 20 prospects from 2014-2019. In that period 87 different players appeared on the lists. Of those, only 20 players had 3 or more 3+ WAR seasons during the 6 years of control. So less than 25% of top 20 prospects actually turned into consistent impact players. And the fact is you would be lucky to get a single top 20 prospect for Skubal, in all likelihood the best you'd get is two top 100 prospects, one of them probably around 50th and the second more of a back half guy. And guess what? Both of those guys are unlikely to turn out to be even average big league starters.
The reality is that the Tigers would not receive a package for Skubal that will have any meaningful impact on the teams outlook for the next 6 seasons. If the Tigers trade Skubal and get one player who gives them 12 WAR over their 6 years of control, that would be an objectively successful return. Sorry, but that level of player is not hard to come by, and that is not an exciting return. I'd rather give it one more shot with Skubal, the franchises outlook over the next 6 years after this one will not change whether they trade Skubal or not.