Tomorrow is Rule 5 protection day. Here's a full list of who is Rule 5 Eligible.
P
Jose Alvarez
Yeremi Bastardo
Austin Bergner
Michael Bienlien
Jorge Boyer
Jaison Brete
Blair Calvo
Jesus Cruz
Daniele Di Monte
Jose Diaz
Wilmer Fenelon
Wilmer Flores
Dario Gardea
Sean Guenther
Layne Henderson
Wilkel Hernandez
Martin Herrera
Zack Hess
Jake Higginbotham
Edgardo Ibarra
Marco Jimenez
Abraham Landaeta
Andrew Magno
Chris Mauloni
Williander Moreno
Tim Naughton
Hendry Nunez
Carlos Pena
Eric Pinales
Angel Reyes
Jose Rivas
Erick Rodriguez
Jesus Rodriguez
Bryan Sammons
Yosber Sanchez
Gabriel Sequeira
Ted Stuka
Bryce Tassin
Matt Walker
Adam Wolf
Aneurys Zabala
C
Eliezer Alfonzo
Daneurys De La Cruz
Dillon Dingler
Ricardo Hurtado
Samuel Rojas
Newremberg Rondon
Sergio Tapia
Eduardo Valencia
IF
Angel Cruz
Geury Estevez
Alvaro Gonzalez
Jake Holton
Corey Joyce
Carlos Mendoza
Andrew Navigato
Quincy Nieporte
Adinso Reyes
Gage Workman
OF
Lazaro Benitez
Danny Cabrera
Roberto Campos
Trei Cruz
Raudy De Los Santos
Iverson Leonardo
Abelaldo Lopez
Jesus Machado
Jose Ochoa
Jose Reina
Manuel Sequera
The only two I would keep are Dingler and Flores. One thing I hope the transaction logs cover is the minor league protection. You can protect up to 38 players from the Minor League phase, but you probably don't want to fill all those spots up, because you also need to make room for any players you outright between now and the Rule 5 draft, any minor league free agents signed between now and the Rule 5 draft, and any players you want to take in the minor league phase.
A lot of players will be clearing waivers tomorrow. There's a decent chance the Tigers claim at least one.
Tomorrow is the last day players added to the 40 man roster since August 15 can be outrighted until March. Same for injured players. Those players can still be non-tendered Friday.
A player DFA'ed tomorrow can be non-tendered on Friday (which may be beneficial if you have a deal in place with them because it bypasses waivers).