Guess I don't see these signs pointing to a Packers victory. Most of the injured players are rotational players. Look at when the Lions played the Packers in week 9. Wingo and Paschal were out just like they are now. Their starting edge players were Muhammad and Isaiah Thomas. They've now upgrade Thomas to Smith. Reader and Levi are the only ones on the DL who played but aren't available. They have since added Smith and Martin.
The secondary is completely intact. Just exchange Rakestraw for Moseley. Keep in mind Branch missed half the game.
On linebacker, Rodriguez was out back in week 9 just like he is this week. Only key piece is Anzalone. They added Alexander. Possibly Adams gets some snaps here as well. It's thin but not terrible.
To recap, Paschal, Wingo, Rodriguez were all out the first time around. They are only missing Anzalone and Reader from the first time they played but have since added Smith (which has been a big addition), Martin, Alexander, and Adams.