The Athletic has an article on realignment following the commissioner's interview during the Little League World Series this past weekend. Their writers have come up with a couple of plausible scenarios.
https://www.nytimes.com/athletic/6560635/2025/08/19/mlb-expansion-realignment-leagues-projection/?source=athletic_pulsenewsletter&campaign=14564600&userId=213687
One would be two leagues with four divisions
AL East
Baltimore, Boston, NY Yankees, Toronto
AL West
Las Vegas, LA Angels, Expansion (Salt Lake or Portland) Seattle
AL North
White Sox, Cleveland, Detroit, Minnesota
AL South
Colorado, Houston, Kansas City, Texas ( The Rockies change leagues)
NL East
Mets, Philadelphia, Pittsburgh, Washington
NL West
Arizona, Dodgers, San Diego, San Francisco
NL North
Cubs, Cincinnati, Milwaukee, St Louis
NL South
Atlanta, Miami, Tampa, Expansion (Nashville, North Carolina)