I belong to a facebook group called Historic Film Locations where they post before/after shots. There was one of the truck chase scene from the first movie. I always thought it was gratiot but it turns out it was not only Grand River, but a portion I drive on a lot when I go to events at the stadiums or theaters.
This is on GR right as you exit off the lodge. The Motor Casino would be right behind you on the right. Up ahead is 75 and on the left would be the "District Detroit", er, I mean the parking lots.
The continuity is off though because where the truck ends up is off Michigan Ave and 30th street, just west of the Corktown area... so not really in the direction they are going at all.